PMS AND PMDD
INFERTILITY AND MENTAL HEALTH
PSYCHIATRIC ILLNESS DURING PREGNANCY
Miuli A, Pettorruso M, Stefanelli G, Giovannetti G, Cavallotto C, Susini O, Pasino A, Bubbico G, De Risio L, Petta GD, Sensi SL, D’Antonio F, Martinotti G.
Psychiatry Res. 2023 May 22;326:115251.
Eleven studies reported moms experienced mild unwanted effects; not one of the included studies reported major unwanted effects for newborns.
Zingg A, Singh T, Franklin A, Ross A, Selvaraj S, Refuerzo J, Myneni S.
BMC Pregnancy Childbirth. 2023 Jun 3;23(1):411.
Association of serum folate levels while pregnant and prenatal depression.
Avalos LA, Nance N, Caan B, Sujan AC, Uriu-Adams JY, Li DK, Quesenberry CP, Hedderson MM.
J Matern Fetal Neonatal Med. 2023 Dec;36(1):1-4.
Of the sample, 13% had prenatal depression. Combined low/medium folate tertiles was related to prenatal depression (adjusted relative risk [aRR] = 1.97, 95% confidence interval [CI]: 0.93-4.18), although results didn’t reach statistical significance. This relationship was stronger amongst women with obese/obesity than women with normal weight (aRR: 2.61, 95% CI: 1.01-6.71 and aRR: 1.50, 95% CI: 0.34-6.66, respectively).
Magee KE, Qu Y, Cheng Y, Hipwell AE, Levine MD.
Int J Eat Disord. 2023 Jun 2.
High levels of lifetime depressive symptoms may increase vulnerability to future lack of control over eating (LOC) prior to first pregnancy, suggesting potential targets for interventions to enhance maternal health.
Serra R, Giacchetti N, Bersani FS, Cappannini G, Martucci M, Panfili M, Sogos C, Aceti F.
BMC Pregnancy Childbirth. 2023 May 25;23(1):382.
Couple relation and neuroticism traits are individual aspects related to depressive symptoms within the perinatal period. The family of origin also plays an indirect role on perinatal depressive symptoms.
MEDICATIONS AND PREGNANCY
Szpunar MJ, Freeman MP, Kobylski LA, Rossa ET, Gaccione P, Chitayat D, Viguera AC, Cohen LS.
J Clin Psychopharmacol. 2023 May 29.
The percentages ratio of a serious malformation amongst infants after first-trimester exposure to any stimulant was 0.39 (95% confidence interval, 0.09-1.61) compared with controls.
POSTPARTUM PSYCHIATRIC ILLNESS
Daehn D, Martens C, Loew V, Kemmler L, Rudolf S, Kochen E, Renneberg B, Pawils S.
BMC Pregnancy Childbirth. 2023 May 31;23(1):402.
SmartMoms is a German mobile web application (web app) designed to tell women about postpartum depression, support them, and supply an easily accessible self-screening instrument.
Association of Recent Fatherhood With Antidepressant Treatment Initiation Amongst Men in the UK.
Smith HC, Petersen I, Schartau P.
JAMA Netw Open. 2023 May 1;6(5):e2316105.
This study suggests that recently having a baby was not related to a rise in antidepressant treatment amongst men, but previous antidepressant treatment in fathers was strongly related to treatment after childbirth (aPRR, 32.31).
Shorey S, Downe S, Chua JYX, Byrne SO, Fobelets M, Lalor JG.
Trauma Violence Abuse. 2023 Jul;24(3):1238-1253.
Psychological interventions were more practical in reducing fear of childbirth and improving PTSD symptoms in comparison with anxiety and depression. Greater improvement in depression was reported at 3-8 weeks’ follow-up than at immediate post-intervention. Subgroup analyses showed that technology-based interventions were feasible, and indicated interventions were more practical than selective interventions. Conducting future interventions in additional realms, engaging and including fathers more actively, incorporating each personalized skilled therapy and informal peer support, striving for flexibility and convenience, in addition to addressing topics on self-doubt and coping skills can improve current interventions.
Safety of Brexanolone in Adults with Postpartum Depression: Postmarketing Surveillance Data.
Garafola S, Shiferaw E, Dev V.
Drugs Real World Outcomes. 2023 Jun 6.
Overall, 499 patients received brexanolone on this postmarketing surveillance evaluation. There have been 396 total AEs: 15 serious unlisted, 2 serious listed, 346 nonserious unlisted, and 33 nonserious listed. In total, two serious and one nonserious listed excessive sedation AEs were reported-all resolved by stopping infusion and didn’t require any treatment; no lack of consciousness AEs were received.
The Effects of Perceived Social Support on Postpartum Anxiety: A Moderated Mediation Model.
Yan P, Xu J. Matern Child Health J. 2023 Aug;27(8):1426-1433.
Self-esteem partially mediated the connection between perceived social support and postnatal anxiety, and this mediating process was moderated by optimism.
MEDICATIONS AND BREASTFEEDING
Monfort A, Cardoso E, Eap CB, Fischer Fumeaux CJ, Graz MB, Morisod Harari M, Weisskopf E, Gandia P, Allegaert K, Nordeng H, Hascoët JM, Claris O, Epiney M, Csajka C, Guidi M, Ferreira E, Panchaud A. Front Psychiatry. 2023 May 18;14:1167870.
PERINATAL SUBSTANCE USE
Brown QL, Shmulewitz D, Sarvet AL, Young-Wolff KC, Howard T, Hasin DS.
Drug Alcohol Depend. 2023 Jul 1;248:109940.
The prevalence of past-year cannabis use and CUD was 9.8% and three.2%, respectively. The percentages of cannabis use (aORs range 2.10-3.87) and CUD (aORs range 2.55-10.44) were higher amongst women with versus with none past-year mood, anxiety or posttraumatic stress disorders or any lifetime personality disorder.
Sujan AC, Alexeeff SE, Slama N, Avalos LA, Adams SR, Conway A, Ansley D, Young-Wolff KC.
J Addict Med. 2023 May-Jun 01;17(3):e141-e147.
This study identified the next 4 latent groups with different patterns of substance use: ( a ) predominantly alcohol and no other substances (9.30%), ( b ) predominantly cannabis and no other substances (4.88%), ( c ) predominantly nicotine and a few pharmaceutical opioids (1.09%), and ( d ) high-polysubstance (alcohol, cannabis, nicotine, and stimulants; 0.36%); ( e ) no prenatal substance use (84.37%).
A scientific review of in utero cannabis exposure and risk for structural birth defects.
Sujan AC, Pal A, Avalos LA, Young-Wolff KC.
Front Pediatr. 2023 May 25;11:1149401.
Throughout the 12 articles reviewed, 4 reported on cardiac malformations, three reported on central nervous system malformations, one reported on eye malformations, three reported on gastrointestinal malformations, one reported on genitourinary malformations, one reported on musculoskeletal malformations, and two reported on orofacial malformations.
MATERNAL MENTAL HEALTH AND CHILD OUTCOMES
Baird H, Harris RA, Santos HP Jr.
Matern Child Health J. 2023 Jun 6.
Across the studies, this review identified a relationship between limited maternal responsiveness as a consequence of postpartum depression and a decrease in full IQ scores in younger children. Male children were found to be more sensitive to the postpartum depression, leading to a decrease in IQs, compared to female children.
Na X, Glasier CM, Andres A, Bellando J, Chen H, Gao W, Livingston LW, Badger TM, Ou X.
Cereb Cortex. 2023 May 22:bhad176.
Significant negative correlations were identified between neonatal brain functional connectivity and mother’s Beck Depression Inventory-II scores within the third trimester, but not in the primary or second trimester. Higher depressive symptoms in the course of the third trimester of pregnancy were related to lower neonatal brain functional connectivity within the frontal lobe and between frontal/temporal lobe and occipital lobe, indicating a possible impact of maternal depressive symptoms on offspring brain development, even within the absence of clinical depression.
MENOPAUSE AND MENTAL HEALTH
OTHER TOPICS IN WOMEN’S MENTAL HEALTH